From Wikipedia, the free encyclopedia
Takotsubo cardiomyopathy, also known as stress cardiomyopathy, is a type of non-ischemic cardiomyopathy in which there is a sudden temporary weakening of the muscular portion of the heart. This weakening may be triggered by emotional stress, such as the death of a loved one, a break-up, or constant anxiety. This leads to one of the common names, Broken Heart Syndrome. Stress cardiomyopathy is now a well-recognized cause of acute heart failure, lethal ventricular arrhythmias, and ventricular rupture.
The name “Takotsubo syndrome” comes from the Japanese word for a kind of octopus trap (ja), because the left ventricle takes on a shape resembling a fishing pot.
Signs and symptoms
The typical presentation of Takotsubo cardiomyopathy is a sudden onset of chest pain associated with ECG changes mimicking a myocardial infarction of the anterior wall. During the course of evaluation of the patient, a bulging out of the left ventricular apex with a hypercontractile base of the left ventricle is often noted. It is the hallmark bulging out of the apex of the heart with preserved function of the base that earned the syndrome its name “tako tsubo”, or octopus pot in Japan, where it was first described.
Debbie Reynolds (Mary Frances Reynolds) –
April 1, 1932 – December 28, 2016 (aged 84)
Source: edited from Wikipedia
Mary Frances “Debbie” Reynolds (April 1, 1932 – December 28, 2016) was an American actress, singer, businesswoman, film historian, and humanitarian. She was nominated for the Golden Globe Award for Most Promising Newcomer for her portrayal of Helen Kane in the 1950 film Three Little Words, and her breakout role was her first leading role, as Kathy Selden in Singin’ in the Rain (1952). Other successes include The Affairs of Dobie Gillis (1953), Susan Slept Here (1954), Bundle of Joy (1956 Golden Globe nomination), The Catered Affair (1956 National Board of Review Best Supporting Actress Winner), and Tammy and the Bachelor (1957), in which her performance of the song “Tammy” reached number one on the Billboard music charts. In 1959, she released her first pop music album, titled Debbie. . . .
Death and legacy
On December 23, 2016, Reynolds’s daughter, actress and writer Carrie Fisher, suffered a medical emergency on a transatlantic flight from London to Los Angeles, and died on December 27 at the age of 60. The following day Reynolds was hospitalized at Cedars-Sinai Medical Center in Los Angeles, after suffering a “severe stroke”, according to son Todd Fisher. Later that afternoon, Reynolds died in the hospital.
Carrie Frances Fisher (October 21, 1956 – December 27, 2016) was an American actress, writer, and humorist. Fisher was the daughter of Eddie Fisher and Debbie Reynolds. She was known for playing Princess Leia in the Star Wars film series. Her other film roles included Shampoo (1975), The Blues Brothers (1980), Hannah and Her Sisters (1986), The ‘Burbs (1989), and When Harry Met Sally… (1989).
Bipolar disorder and drug use
In appearances on 20/20 and The Secret Life of the Manic Depressive with Stephen Fry, Fisher publicly discussed her diagnosis of bipolar disorder and her addictions to cocaine and prescription medication. She said her drug use was a form of self-medication; she used pain medication such as Percodan to “dial down” the manic aspect of her bipolar disorder. “Drugs made me feel normal,” she explained to Psychology Today in 2001. “They contained me.” She discussed her 2008 memoir Wishful Drinking and various topics in it with Matt Lauer on NBC’s Today that same year, and also revealed that she would have turned down the role of Princess Leia had she realized it would give her the celebrity status that made her parents’ lives difficult. This interview was followed by a similar appearance on The Late Late Show with Craig Ferguson on December 12, 2008, where she discussed her electroconvulsive therapy (ECT) treatments. At one point, she received ECT every six weeks to “blow apart the cement” in her brain. In 2014, she said she was no longer receiving the treatment.
Fisher revealed in another interview that she used cocaine during the filming of The Empire Strikes Back. “Slowly, I realized I was doing a bit more drugs than other people and losing my choice in the matter,” she noted. In 1985, after months of sobriety, she accidentally overdosed on a combination of prescription medication and sleeping pills. She was rushed to the hospital, creating the turn of events that led to much of the material in her novel and screenplay, Postcards from the Edge. Asked why she did not take on the role of her story’s protagonist, named Suzanne, in the film version, Fisher remarked, “I’ve already played Suzanne.”
Garry Emmanuel Shandling (November 29, 1949 – March 24, 2016) was an American stand-up comedian, actor, writer, and producer, best known for his work in It’s Garry Shandling’s Show and The Larry Sanders Show.
On March 24, 2016, Shandling died in his home in Los Angeles, California at age 66. The Los Angeles Police Department reported that he suddenly collapsed in his home and was rushed to a hospital, suffering from an apparent medical emergency. However, by the time the paramedics had arrived, Shandling was already unconscious. In December 2016, the coroner said the cause of death was a blood clot in his lungs following deep vein thrombosis in his legs.
above source: Wikipedia
Obtained by PEOPLE, the 66-year-old actor’s autopsy report states the star of The Larry Sanders Show had a combination of drugs in his system, including Xanax and opiates (codeine/morphine and hydrocodone), at the time of his March death.