From Wikipedia, the free encyclopedia
, M.D., (born 13 November 1935, The Hague) is a Dutch cardiologist who is considered one of the founding fathers of the cardiology subspecialty known as clinical cardiac electrophysiology. Clinical cardiac electrophysiology enables patients with cardiac arrhythmmias to be subjected to catheter electrode mapping and stimulation studies. Paul Puech, first in Mexico and later in France; Benjamin Scherlag and Onkar Narula in the USA; and Dirk Durrer and Philippe Coumel in Europe were the field’s pioneers in the 1950s and 1960s. The field’s second wave of innovators used these techniques to unravel the mechanisms of tachycardia in humans and set the bases for their treatment. Among them, Hein Wellens in Europe and Kenneth Rosen, John Gallagher, and Mark Josephson in the USA had the greatest impact as researchers and teachers. Josephson is the author of the first and most successful textbook of clinical cardiac electrophysiology, now in its fourth edition.
Wellens, known among European cardiologists as “the giant of Maastricht”, has for many years been associated with the University of Limburg School of Medicine in Maastricht, Netherlands. At his department of cardiology, many future clinical cardiac electrophysiologists trained from 1976 until his retirement in 2002.
As a pupil and collaborator of the late Professor Dirk Durrer in Amsterdam, Dr. Wellens was involved in the early developments in programmed electrical stimulation of the heart in patients with the Wolff-Parkinson-White syndrome. In these patients, cardiac arrhythmias it was shown for the very first time that were first shown to be possibly initiated and terminated by critically timed premature beats. In 1971, he reported on the use of programmed electrical stimulation of the heart in patients with atrial flutter, AV nodal tachycardia, and accessory atrioventricular connections. In 1972, he showed that the arrhythmia of patients with ventricular tachycardia could also reproducibly be initiated and terminated by timed premature stimuli. These investigations were the basis for the new surgical and pacing approaches to the treatment of cardiac arrhythmias that became known as “cardiac electrophysiology”. to be Wellens also demonstrated that the reproducible initiation and termination of arrhythmias by programmed electrical stimulation of the heart allowed the study of the effect of antiarrhythmic drugs on the mechanism of the arrhythmia. In 1977, he moved to the new University of Limburg in Maastricht, Netherlands, to develop academic cardiology there. Starting from scratch, he created an internationally known center for the study and treatment of cardiac arrhythmias.
Willem Einthoven (21 May 1860 – 29 September 1927) was a Dutch doctor and physiologist. He invented the first practical electrocardiogram (ECG or EKG) in 1903 and received the Nobel Prize in Medicine in 1924 for it.
Einthoven was born in Semarang on Java in the Dutch East Indies (now Indonesia), the son of Louise Marie Mathilde Caroline (de Vogel) and Jacob Einthoven. His father, a doctor, died when Einthoven was a child. His mother returned to the Netherlands with her children in 1870 and settled in Utrecht. His father was of Jewish and Dutch descent, and his mother’s ancestry was Dutch and Swiss. In 1885, Einthoven received a medical degree from the University of Utrecht. He became a professor at the University of Leiden in 1886.
In 1902, he became member of the Royal Netherlands Academy of Arts and Sciences.
He died in Leiden in the Netherlands and is buried in the graveyard of the Reformed Church at 6 Haarlemmerstraatweg in Oegstgeest.
From Wikipedia, the free encyclopedia taken on August 26, 2016
Pierre-Simon, marquis de Laplace (/ləˈplɑːs/; French: [pjɛʁ simɔ̃ laplas]; 23 March 1749 – 5 March 1827) was an influential French scholar whose work was important to the development of mathematics, statistics, physics, and astronomy. He summarized and extended the work of his predecessors in his five-volume Mécanique Céleste (Celestial Mechanics) (1799–1825). This work translated the geometric study of classical mechanics to one based on calculus, opening up a broader range of problems. In statistics, the Bayesian interpretation of probability was developed mainly by Laplace.
Pierre-Simon Laplace (1749–1827). Posthumous portrait by
Jean-Baptiste Paulin Guérin, 1838.
From Wikipedia, the free encyclopedia on August 26, 2016
Jean Léonard Marie Poiseuille
22 April 1797
26 December 1869 (aged 72) Paris
physicist and physiologist
Jean Léonard Marie Poiseuille (French: [pwazœj]; 22 April 1797 – 26 December 1869) was a French physicist and physiologist.
Poiseuille was born in Paris, France and he died there on 26 December 1869.
From 1815 to 1816 he studied at the École Polytechnique in Paris. He was trained in physics and mathematics. In 1828 he earned his D.Sc. degree with a dissertation entitled Recherches sur la force du coeur aortique. He was interested in the flow of human blood in narrow tubes.
WASHINGTON (AP) — Sudden cardiac arrest may not always be so sudden: New research suggests a lot of people may ignore potentially life-saving warning signs hours, days, even a few weeks before they collapse.
Cardiac arrest claims about 350,000 U.S. lives a year. It’s not a heart attack, but worse: The heart abruptly stops beating, its electrical activity knocked out of rhythm. CPR can buy critical time, but so few patients survive that it’s been hard to tell if the longtime medical belief is correct that it’s a strike with little or no advance warning.
An unusual study that has closely tracked sudden cardiac arrest in Portland, Oregon, for over a decade got around that roadblock, using interviews with witnesses, family and friends after patients collapse and tracking down their medical records.
About half of middle-aged patients for whom symptom information could be found had experienced warning signs, mostly chest pain or shortness of breath, in the month before suffering a cardiac arrest, researchers reported Monday. The research offers the possibility of one day preventing some cardiac arrests if doctors could figure out how to find and treat the people most at risk.